4ij5: Difference between revisions

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==Crystal Structure of a Novel-type Phosphoserine Phosphatase from <i>Hydrogenobacter thermophilus</i> TK-6==
==Crystal Structure of a Novel-type Phosphoserine Phosphatase from <i>Hydrogenobacter thermophilus</i> TK-6==
<StructureSection load='4ij5' size='340' side='right' caption='[[4ij5]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='4ij5' size='340' side='right'caption='[[4ij5]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ij5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hydtt Hydtt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IJ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IJ5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ij5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hydrogenobacter_thermophilus_TK-6 Hydrogenobacter thermophilus TK-6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IJ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IJ5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ij6|4ij6]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ij5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ij5 OCA], [https://pdbe.org/4ij5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ij5 RCSB], [https://www.ebi.ac.uk/pdbsum/4ij5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ij5 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pspA, pgmA, HTH_0103, Hydth_0104 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=608538 HYDTT])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoserine_phosphatase Phosphoserine phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.3 3.1.3.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ij5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ij5 OCA], [http://pdbe.org/4ij5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ij5 RCSB], [http://www.ebi.ac.uk/pdbsum/4ij5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ij5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PSPA_HYDTT PSPA_HYDTT]] Catalyzes the dephosphorylation of L-phosphoserine to serine and inorganic phosphate. Is poorly or not active toward D-phosphoserine, DL-phosphothreonine, 3-phosphoglycerate, para-nitrophenylphosphate, and fructose-6-phosphate. Does not display phosphoglycerate mutase activity.  
[https://www.uniprot.org/uniprot/PSPA_HYDTT PSPA_HYDTT] Catalyzes the dephosphorylation of L-phosphoserine to serine and inorganic phosphate. Is poorly or not active toward D-phosphoserine, DL-phosphothreonine, 3-phosphoglycerate, para-nitrophenylphosphate, and fructose-6-phosphate. Does not display phosphoglycerate mutase activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hydtt]]
[[Category: Hydrogenobacter thermophilus TK-6]]
[[Category: Phosphoserine phosphatase]]
[[Category: Large Structures]]
[[Category: Arai, H]]
[[Category: Arai H]]
[[Category: Chiba, Y]]
[[Category: Chiba Y]]
[[Category: Horita, S]]
[[Category: Horita S]]
[[Category: Igarashi, Y]]
[[Category: Igarashi Y]]
[[Category: Ishii, M]]
[[Category: Ishii M]]
[[Category: Nagata, K]]
[[Category: Nagata K]]
[[Category: Ohtsuka, J]]
[[Category: Ohtsuka J]]
[[Category: Tanokura, M]]
[[Category: Tanokura M]]
[[Category: Hydrolase]]
[[Category: Phosphatase]]

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