4jh4: Difference between revisions
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==Crystal Structure of FosB from Bacillus cereus with Nickel and Fosfomycin== | ==Crystal Structure of FosB from Bacillus cereus with Nickel and Fosfomycin== | ||
<StructureSection load='4jh4' size='340' side='right' caption='[[4jh4]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='4jh4' size='340' side='right'caption='[[4jh4]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4jh4]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4jh4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus_ATCC_10987 Bacillus cereus ATCC 10987]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JH4 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FCN:FOSFOMYCIN'>FCN</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FCN:FOSFOMYCIN'>FCN</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jh4 OCA], [https://pdbe.org/4jh4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jh4 RCSB], [https://www.ebi.ac.uk/pdbsum/4jh4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jh4 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/FOSB_BACC1 FOSB_BACC1] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Bacillus cereus ATCC 10987]] | ||
[[Category: Armstrong | [[Category: Large Structures]] | ||
[[Category: Cook | [[Category: Armstrong RN]] | ||
[[Category: Harp | [[Category: Cook PD]] | ||
[[Category: Jagessar | [[Category: Harp J]] | ||
[[Category: Keithly | [[Category: Jagessar K]] | ||
[[Category: Thompson | [[Category: Keithly ME]] | ||
[[Category: Thompson MK]] | |||