4jh4: Difference between revisions

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==Crystal Structure of FosB from Bacillus cereus with Nickel and Fosfomycin==
==Crystal Structure of FosB from Bacillus cereus with Nickel and Fosfomycin==
<StructureSection load='4jh4' size='340' side='right' caption='[[4jh4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='4jh4' size='340' side='right'caption='[[4jh4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4jh4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacc1 Bacc1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JH4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JH4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4jh4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus_ATCC_10987 Bacillus cereus ATCC 10987]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JH4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FCN:FOSFOMYCIN'>FCN</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FCN:FOSFOMYCIN'>FCN</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jh1|4jh1]], [[4jh2|4jh2]], [[4jh3|4jh3]], [[4jh5|4jh5]], [[4jh6|4jh6]], [[4jh7|4jh7]], [[4jh8|4jh8]], [[4jh9|4jh9]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jh4 OCA], [https://pdbe.org/4jh4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jh4 RCSB], [https://www.ebi.ac.uk/pdbsum/4jh4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jh4 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fosB, BCE_2111 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=222523 BACC1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jh4 OCA], [http://pdbe.org/4jh4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jh4 RCSB], [http://www.ebi.ac.uk/pdbsum/4jh4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jh4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FOSB_BACC1 FOSB_BACC1]] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity).  
[https://www.uniprot.org/uniprot/FOSB_BACC1 FOSB_BACC1] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacc1]]
[[Category: Bacillus cereus ATCC 10987]]
[[Category: Armstrong, R N]]
[[Category: Large Structures]]
[[Category: Cook, P D]]
[[Category: Armstrong RN]]
[[Category: Harp, J]]
[[Category: Cook PD]]
[[Category: Jagessar, K]]
[[Category: Harp J]]
[[Category: Keithly, M E]]
[[Category: Jagessar K]]
[[Category: Thompson, M K]]
[[Category: Keithly ME]]
[[Category: Bacillithiol-s-transferase]]
[[Category: Thompson MK]]
[[Category: Transferase]]

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