3mvg: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
Line 3: Line 3:
<StructureSection load='3mvg' size='340' side='right' caption='[[3mvg]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
<StructureSection load='3mvg' size='340' side='right' caption='[[3mvg]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3mvg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Iris_x_hollandica Iris x hollandica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MVG FirstGlance]. <br>
<table><tr><td colspan='2'>[[3mvg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Iris_hollandica Iris hollandica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MVG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2b7u|2b7u]], [[1bry|1bry]], [[1ahc|1ahc]], [[1nio|1nio]], [[1rl0|1rl0]], [[2oqa|2oqa]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2b7u|2b7u]], [[1bry|1bry]], [[1ahc|1ahc]], [[1nio|1nio]], [[1rl0|1rl0]], [[2oqa|2oqa]]</td></tr>
Line 22: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Iris x hollandica]]
[[Category: Iris hollandica]]
[[Category: RRNA N-glycosylase]]
[[Category: RRNA N-glycosylase]]
[[Category: Betzel, C]]
[[Category: Betzel, C]]

Revision as of 16:41, 16 January 2019

Native structure of IRIP, a type I ribosome inactivating protein from Iris hollandica var. at 1.25 ANative structure of IRIP, a type I ribosome inactivating protein from Iris hollandica var. at 1.25 A

Structural highlights

3mvg is a 2 chain structure with sequence from Iris hollandica. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:rRNA N-glycosylase, with EC number 3.2.2.22
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Publication Abstract from PubMed

The most abundant protein of Iris bulbs has been identified as a type 1 ribosome-inactivating protein (RIP). Analysis of the purified proteins and molecular cloning of the corresponding cDNAs demonstrated that this type 1 RIP is a mixture of three isoforms that exhibit a high degree of sequence identity and have similar, though not identical, ribosome-inactivating and polynucleotide:adenosine glycosidase activities. The accumulation of large quantities of type 1 RIP in a vegetative storage organ suggests that this presumed defence-related protein also plays a role in the nitrogen-storage metabolism of the bulb.

Type 1 ribosome-inactivating proteins are the most abundant proteins in iris (Iris hollandica var. Professor Blaauw) bulbs: characterization and molecular cloning.,Van Damme EJ, Barre A, Barbieri L, Valbonesi P, Rouge P, Van Leuven F, Stirpe F, Peumans WJ Biochem J. 1997 Jun 15;324 ( Pt 3):963-70. PMID:9210423[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

  1. Van Damme EJ, Barre A, Barbieri L, Valbonesi P, Rouge P, Van Leuven F, Stirpe F, Peumans WJ. Type 1 ribosome-inactivating proteins are the most abundant proteins in iris (Iris hollandica var. Professor Blaauw) bulbs: characterization and molecular cloning. Biochem J. 1997 Jun 15;324 ( Pt 3):963-70. PMID:9210423

3mvg, resolution 1.25Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA