4j2r: Difference between revisions

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==Middle domain of influenza A virus RNA-dependent polymerase PB2==
==Middle domain of influenza A virus RNA-dependent polymerase PB2==
<StructureSection load='4j2r' size='340' side='right' caption='[[4j2r]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
<StructureSection load='4j2r' size='340' side='right'caption='[[4j2r]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4j2r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/I34a1 I34a1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J2R FirstGlance]. <br>
<table><tr><td colspan='2'>[[4j2r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/Puerto_Rico/8/1934(H1N1)) Influenza A virus (A/Puerto Rico/8/1934(H1N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J2R FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3cw4|3cw4]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j2r OCA], [https://pdbe.org/4j2r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j2r RCSB], [https://www.ebi.ac.uk/pdbsum/4j2r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j2r ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PB2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=211044 I34A1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j2r OCA], [http://pdbe.org/4j2r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j2r RCSB], [http://www.ebi.ac.uk/pdbsum/4j2r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j2r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PB2_I34A1 PB2_I34A1]] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity).  
[https://www.uniprot.org/uniprot/PB2_I34A1 PB2_I34A1] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity).
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[RNA polymerase|RNA polymerase]]
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: I34a1]]
[[Category: Large Structures]]
[[Category: Hatakeyama, D]]
[[Category: Hatakeyama D]]
[[Category: Kuzuhara, T]]
[[Category: Kuzuhara T]]
[[Category: Qiu, H]]
[[Category: Qiu H]]
[[Category: Tsuge, H]]
[[Category: Tsuge H]]
[[Category: Tsumori, Y]]
[[Category: Tsumori Y]]
[[Category: Tsurumura, T]]
[[Category: Tsurumura T]]
[[Category: Cap-binding domain]]
[[Category: Cap-snatching]]
[[Category: Viral protein]]

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