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==EDTA-free crystal structure of the mutant C221D of carbapenemase CphA from Aeromonas hydrophila== | ==EDTA-free crystal structure of the mutant C221D of carbapenemase CphA from Aeromonas hydrophila== | ||
<StructureSection load='3sw3' size='340' side='right' caption='[[3sw3]], [[Resolution|resolution]] 2.35Å' scene=''> | <StructureSection load='3sw3' size='340' side='right'caption='[[3sw3]], [[Resolution|resolution]] 2.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3sw3]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3sw3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"aeromonas_liquefaciens"_kluyver_and_van_niel_1936 "aeromonas liquefaciens" kluyver and van niel 1936]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SW3 FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1x8g|1x8g]], [[1x8h|1x8h]], [[3t9m|3t9m]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1x8g|1x8g]], [[1x8h|1x8h]], [[3t9m|3t9m]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cphA ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cphA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=644 "Aeromonas liquefaciens" Kluyver and van Niel 1936])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sw3 OCA], [https://pdbe.org/3sw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sw3 RCSB], [https://www.ebi.ac.uk/pdbsum/3sw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sw3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/BLAB_AERHY BLAB_AERHY]] Can hydrolyze carbapenem compounds. | ||
==See Also== | ==See Also== | ||
*[[Beta-lactamase|Beta-lactamase]] | *[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Aeromonas liquefaciens kluyver and van niel 1936]] | [[Category: Aeromonas liquefaciens kluyver and van niel 1936]] | ||
[[Category: Beta-lactamase]] | [[Category: Beta-lactamase]] | ||
[[Category: Large Structures]] | |||
[[Category: Delbruck, H]] | [[Category: Delbruck, H]] | ||
[[Category: Hoffmann, K M.V]] | [[Category: Hoffmann, K M.V]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 11:12, 29 June 2022
EDTA-free crystal structure of the mutant C221D of carbapenemase CphA from Aeromonas hydrophilaEDTA-free crystal structure of the mutant C221D of carbapenemase CphA from Aeromonas hydrophila
Structural highlights
Function[BLAB_AERHY] Can hydrolyze carbapenem compounds. See Also |
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