4mm2: Difference between revisions
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==Crystal structure of yeast primase catalytic subunit== | ==Crystal structure of yeast primase catalytic subunit== | ||
<StructureSection load='4mm2' size='340' side='right' caption='[[4mm2]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='4mm2' size='340' side='right'caption='[[4mm2]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4mm2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MM2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MM2 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4mm2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MM2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MM2 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRI1, YIR008C, YIB8C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mm2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mm2 OCA], [http://pdbe.org/4mm2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mm2 RCSB], [http://www.ebi.ac.uk/pdbsum/4mm2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mm2 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mm2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mm2 OCA], [http://pdbe.org/4mm2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mm2 RCSB], [http://www.ebi.ac.uk/pdbsum/4mm2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mm2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/PRI1_YEAST PRI1_YEAST]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48. | [[http://www.uniprot.org/uniprot/PRI1_YEAST PRI1_YEAST]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48. | ||
==See Also== | |||
*[[RNA polymerase|RNA polymerase]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Baker's yeast]] | |||
[[Category: Large Structures]] | |||
[[Category: An, J Y]] | [[Category: An, J Y]] | ||
[[Category: Eom, S H]] | [[Category: Eom, S H]] | ||