4nat: Difference between revisions

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 ==Inhibitors of 4-Phosphopanthetheine Adenylyltransferase==
-<StructureSection load='4nat' size='340' side='right' caption='[[4nat]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
+<StructureSection load='4nat' size='340' side='right'caption='[[4nat]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4nat]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Staaw Staaw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NAT FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4nat]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MW2 Staphylococcus aureus subsp. aureus MW2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NAT FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2W5:(1R,2R)-N-(3,4-DICHLOROBENZYL)-2-(4,6-DIMETHOXYPYRIMIDIN-2-YL)CYCLOHEXANECARBOXAMIDE'>2W5</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2W5:(1R,2R)-N-(3,4-DICHLOROBENZYL)-2-(4,6-DIMETHOXYPYRIMIDIN-2-YL)CYCLOHEXANECARBOXAMIDE'>2W5</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nah|4nah]], [[4nau|4nau]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nat OCA], [https://pdbe.org/4nat PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nat RCSB], [https://www.ebi.ac.uk/pdbsum/4nat PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nat ProSAT]</span></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">coaD, MW1007 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196620 STAAW])</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantetheine-phosphate_adenylyltransferase Pantetheine-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.3 2.7.7.3] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nat OCA], [http://pdbe.org/4nat PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nat RCSB], [http://www.ebi.ac.uk/pdbsum/4nat PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nat ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/COAD_STAAW COAD_STAAW]] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).
+[https://www.uniprot.org/uniprot/COAD_STAAW COAD_STAAW] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 25: / Line 22: @@
 __TOC__
 </StructureSection>
-[[Category: Pantetheine-phosphate adenylyltransferase]]
+[[Category: Large Structures]]
-[[Category: Staaw]]
+[[Category: Staphylococcus aureus subsp. aureus MW2]]
-[[Category: Lahiri, S D]]
+[[Category: Lahiri SD]]
-[[Category: Coabc]]
-[[Category: Coad]]
-[[Category: Cytosolic]]
-[[Category: Panthetheine]]
-[[Category: Phosphopanthetheine adenylyltransferase]]
-[[Category: Transferase-transferase inhibitor complex]]