4hdb: Difference between revisions
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==Crystal Structure of HIV-1 protease mutants D30N complexed with inhibitor GRL-0519== | ==Crystal Structure of HIV-1 protease mutants D30N complexed with inhibitor GRL-0519== | ||
<StructureSection load='4hdb' size='340' side='right' caption='[[4hdb]], [[Resolution|resolution]] 1.49Å' scene=''> | <StructureSection load='4hdb' size='340' side='right'caption='[[4hdb]], [[Resolution|resolution]] 1.49Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4hdb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HDB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HDB FirstGlance]. <br> | <table><tr><td colspan='2'>[[4hdb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HDB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HDB FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=G52:(3R,3AS,3BR,6AS,7AS)-OCTAHYDRODIFURO[2,3-B 3,2-D]FURAN-3-YL+[(1S,2R)-1-BENZYL-2-HYDROXY-3-{[(4-METHOXYPHENYL)SULFONYL](2-METHYLPROPYL)AMINO}PROPYL]CARBAMATE'>G52</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=G52:(3R,3AS,3BR,6AS,7AS)-OCTAHYDRODIFURO[2,3-B 3,2-D]FURAN-3-YL+[(1S,2R)-1-BENZYL-2-HYDROXY-3-{[(4-METHOXYPHENYL)SULFONYL](2-METHYLPROPYL)AMINO}PROPYL]CARBAMATE'>G52</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ok9|3ok9]], [[4heg|4heg]], [[4hdf|4hdf]], [[4hdp|4hdp]], [[4he9|4he9]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ok9|3ok9]], [[4heg|4heg]], [[4hdf|4hdf]], [[4hdp|4hdp]], [[4he9|4he9]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11686 HIV-1])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hdb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hdb OCA], [http://pdbe.org/4hdb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hdb RCSB], [http://www.ebi.ac.uk/pdbsum/4hdb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hdb ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hdb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hdb OCA], [http://pdbe.org/4hdb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hdb RCSB], [http://www.ebi.ac.uk/pdbsum/4hdb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hdb ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4hdb" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4hdb" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Hiv-1]] | |||
[[Category: Large Structures]] | |||
[[Category: Agniswamy, J]] | [[Category: Agniswamy, J]] | ||
[[Category: Shen, C H]] | [[Category: Shen, C H]] |