3vpm: Difference between revisions

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== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RIR2_HUMAN RIR2_HUMAN]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.  
[[http://www.uniprot.org/uniprot/RIR2_HUMAN RIR2_HUMAN]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.  
==See Also==
*[[Ribonucleotide reductase|Ribonucleotide reductase]]
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Revision as of 10:56, 22 November 2017

Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutantCrystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant

Structural highlights

3vpm is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:RR2, RRM2 (HUMAN)
Activity:Ribonucleoside-diphosphate reductase, with EC number 1.17.4.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[RIR2_HUMAN] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

3vpm, resolution 2.70Å

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OCA
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