4lm3: Difference between revisions

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 ==Crystal structure of PDE10A2 with fragment ZT464==
-<StructureSection load='4lm3' size='340' side='right' caption='[[4lm3]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
+<StructureSection load='4lm3' size='340' side='right'caption='[[4lm3]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4lm3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LM3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LM3 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4lm3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LM3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LM3 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9ZE:1-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)ETHANONE'>9ZE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9ZE:1-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)ETHANONE'>9ZE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lkq|4lkq]], [[4llj|4llj]], [[4lll|4lll]], [[4llp|4llp]], [[4llx|4llx]], [[4lm0|4lm0]], [[4lm1|4lm1]], [[4lm2|4lm2]], [[4lm4|4lm4]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lm3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lm3 OCA], [https://pdbe.org/4lm3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lm3 RCSB], [https://www.ebi.ac.uk/pdbsum/4lm3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lm3 ProSAT]</span></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDE10A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lm3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lm3 OCA], [http://pdbe.org/4lm3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lm3 RCSB], [http://www.ebi.ac.uk/pdbsum/4lm3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lm3 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/PDE10_HUMAN PDE10_HUMAN]] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.<ref>PMID:17389385</ref>
+[https://www.uniprot.org/uniprot/PDE10_HUMAN PDE10_HUMAN] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.<ref>PMID:17389385</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 22: / Line 20: @@
 ==See Also==
-*[[Phosphodiesterase|Phosphodiesterase]]
+*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Badger, J]]
+[[Category: Large Structures]]
-[[Category: Chie-Leon, B]]
+[[Category: Badger J]]
-[[Category: Logan, C]]
+[[Category: Chie-Leon B]]
-[[Category: Nienaber, V]]
+[[Category: Logan C]]
-[[Category: Sridhar, V]]
+[[Category: Nienaber V]]
-[[Category: Fragment screening]]
+[[Category: Sridhar V]]
-[[Category: Hydrolase]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]