2xu4: Difference between revisions
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==CATHEPSIN L WITH A NITRILE INHIBITOR== | ==CATHEPSIN L WITH A NITRILE INHIBITOR== | ||
<StructureSection load='2xu4' size='340' side='right' caption='[[2xu4]], [[Resolution|resolution]] 1.12Å' scene=''> | <StructureSection load='2xu4' size='340' side='right'caption='[[2xu4]], [[Resolution|resolution]] 1.12Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xu4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XU4 OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[2xu4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XU4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2XU4 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DJT:(2S,4R)-4-(2-CHLOROPHENYL)SULFONYL-1-[1-(4-FLUOROPHENYL)CYCLOPROPYL]CARBONYL-N-[1-(IMINOMETHYL)CYCLOPROPYL]PYRROLIDINE-2-CARBOXAMIDE'>DJT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DJT:(2S,4R)-4-(2-CHLOROPHENYL)SULFONYL-1-[1-(4-FLUOROPHENYL)CYCLOPROPYL]CARBONYL-N-[1-(IMINOMETHYL)CYCLOPROPYL]PYRROLIDINE-2-CARBOXAMIDE'>DJT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mhw|1mhw]], [[1cjl|1cjl]], [[1cs8|1cs8]], [[2vhs|2vhs]], [[1icf|1icf]], [[2xu5|2xu5]], [[2xu1|2xu1]], [[2xu3|2xu3]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mhw|1mhw]], [[1cjl|1cjl]], [[1cs8|1cs8]], [[2vhs|2vhs]], [[1icf|1icf]], [[2xu5|2xu5]], [[2xu1|2xu1]], [[2xu3|2xu3]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_L Cathepsin L], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.15 3.4.22.15] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_L Cathepsin L], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.15 3.4.22.15] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2xu4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xu4 OCA], [http://pdbe.org/2xu4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xu4 RCSB], [http://www.ebi.ac.uk/pdbsum/2xu4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xu4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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==See Also== | ==See Also== | ||
*[[Cathepsin|Cathepsin]] | *[[Cathepsin 3D structures|Cathepsin 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cathepsin L]] | [[Category: Cathepsin L]] | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Banner, D W]] | [[Category: Banner, D W]] | ||
[[Category: Benz, J M]] | [[Category: Benz, J M]] | ||
Revision as of 15:21, 22 July 2020
CATHEPSIN L WITH A NITRILE INHIBITORCATHEPSIN L WITH A NITRILE INHIBITOR
Structural highlights
Function[CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes. See Also |
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