5ive: Difference between revisions

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==Linked KDM5A Jmj Domain Bound to the Inhibitor N8 ( 5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile)==
==Linked KDM5A Jmj Domain Bound to the Inhibitor N8 ( 5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile)==
<StructureSection load='5ive' size='340' side='right' caption='[[5ive]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
<StructureSection load='5ive' size='340' side='right'caption='[[5ive]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ive]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IVE FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ive]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IVE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IVE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6E8:5-METHYL-7-OXO-6-(PROPAN-2-YL)-4,7-DIHYDROPYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE'>6E8</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6E8:5-METHYL-7-OXO-6-(PROPAN-2-YL)-4,7-DIHYDROPYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE'>6E8</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5isl|5isl]], [[5ivb|5ivb]], [[5ivc|5ivc]], [[5ivf|5ivf]], [[5ivj|5ivj]], [[5ivv|5ivv]], [[5ivy|5ivy]], [[5iw0|5iw0]], [[5iwf|5iwf]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5isl|5isl]], [[5ivb|5ivb]], [[5ivc|5ivc]], [[5ivf|5ivf]], [[5ivj|5ivj]], [[5ivv|5ivv]], [[5ivy|5ivy]], [[5iw0|5iw0]], [[5iwf|5iwf]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ive OCA], [http://pdbe.org/5ive PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ive RCSB], [http://www.ebi.ac.uk/pdbsum/5ive PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ive ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KDM5A, JARID1A, RBBP2, RBP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ive FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ive OCA], [http://pdbe.org/5ive PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ive RCSB], [http://www.ebi.ac.uk/pdbsum/5ive PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ive ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 5ive" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ive" style="background-color:#fffaf0;"></div>
==See Also==
*[[Jumonji domain-containing protein 3D structures|Jumonji domain-containing protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Cheng, X]]
[[Category: Cheng, X]]
[[Category: Horton, J R]]
[[Category: Horton, J R]]
[[Category: Demethylase inhibition]]
[[Category: Demethylase inhibition]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

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