5knq: Difference between revisions

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-'''Unreleased structure'''
-The entry 5knq is ON HOLD  until Paper Publication
+==Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with [3S,4R]-(4-(Guanin-9-yl)pyrrolidin-3-yl)oxymethanephosphonic acid and pyrophosphate==
+<StructureSection load='5knq' size='340' side='right' caption='[[5knq]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
-Authors: Eng, W.S., Rejman, D., Keough, D.T., Guddat, L.W.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5knq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KNQ FirstGlance]. <br>
-Description: Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with [3S,4R]-(4-(Guanin-9-yl)pyrrolidin-3-yl)oxymethanephosphonic acid and pyrophosphate
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6W8:[(3~{S},4~{R})-4-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)pyrrolidin-3-yl]oxymethylphosphonic+acid'>6W8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5knp|5knp]], [[5kny|5kny]], [[5knr|5knr]], [[5kns|5kns]], [[5knv|5knv]], [[5knu|5knu]], [[5knt|5knt]], [[5knx|5knx]]</td></tr>
-[[Category: Eng, W.S]]
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hpt, hprT, Rv3624c, MTCY15C10.28 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5knq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knq OCA], [http://pdbe.org/5knq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5knq RCSB], [http://www.ebi.ac.uk/pdbsum/5knq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5knq ProSAT]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
+[[Category: Hypoxanthine phosphoribosyltransferase]]
+[[Category: Myctu]]
+[[Category: Eng, W S]]
+[[Category: Guddat, L W]]
+[[Category: Keough, D T]]
 [[Category: Rejman, D]]
-[[Category: Keough, D.T]]
+[[Category: Complex]]
-[[Category: Guddat, L.W]]
+[[Category: Inhibitor]]
+[[Category: Phosphoribosyltransferase]]
+[[Category: Pyrrolidne nucleoside phosphonate]]
+[[Category: Transferase-inhibitor complex]]