5kht: Difference between revisions

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-'''Unreleased structure'''
-The entry 5kht is ON HOLD  until Jun 15 2018
+==Crystal structure of the N-terminal fragment of tropomyosin isoform Tpm1.1 at 1.5 A resolution==
+<StructureSection load='5kht' size='340' side='right' caption='[[5kht]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5kht]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KHT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KHT FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GCN4, AAS3, ARG9, YEL009C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kht OCA], [http://pdbe.org/5kht PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kht RCSB], [http://www.ebi.ac.uk/pdbsum/5kht PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kht ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/TPM1_HUMAN TPM1_HUMAN]] Left ventricular noncompaction;Familial isolated hypertrophic cardiomyopathy;Familial isolated dilated cardiomyopathy. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[[http://www.uniprot.org/uniprot/TPM1_HUMAN TPM1_HUMAN]] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
-Authors: Kostyukova, A.S., Krieger, I., Yoon, Y.-H., Tolkatchev, D., Samatey, F.A.
+==See Also==
+*[[Tropomyosin|Tropomyosin]]
-Description: Crystal structure of the N-terminal fragment of tropomyosin isoform Tpm1.1 at 1.5 A resolution
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
+[[Category: Human]]
+[[Category: Kostyukova, A S]]
+[[Category: Krieger, I]]
+[[Category: Samatey, F A]]
 [[Category: Tolkatchev, D]]
-[[Category: Kostyukova, A.S]]
+[[Category: Yoon, Y H]]
-[[Category: Yoon, Y.-H]]
+[[Category: Actin-binding protein]]
-[[Category: Krieger, I]]
+[[Category: Coiled coil]]
-[[Category: Samatey, F.A]]
+[[Category: Tropomyosin]]