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==Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with a 2-Fluoro-substituted OBHS derivative== | ==Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with a 2-Fluoro-substituted OBHS derivative== | ||
<StructureSection load='4znh' size='340' side='right' caption='[[4znh]], [[Resolution|resolution]] 1.93Å' scene=''> | <StructureSection load='4znh' size='340' side='right'caption='[[4znh]], [[Resolution|resolution]] 1.93Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4znh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZNH FirstGlance]. <br> | <table><tr><td colspan='2'>[[4znh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZNH FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OBC:2-FLUOROPHENYL+(1S,2R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2-SULFONATE'>OBC</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OBC:2-FLUOROPHENYL+(1S,2R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2-SULFONATE'>OBC</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pp6|4pp6]], [[4zn7|4zn7]], [[4zn9|4zn9]], [[4zns|4zns]], [[4znt|4znt]], [[4znu|4znu]], [[4znv|4znv]], [[4znw|4znw]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pp6|4pp6]], [[4zn7|4zn7]], [[4zn9|4zn9]], [[4zns|4zns]], [[4znt|4znt]], [[4znu|4znu]], [[4znv|4znv]], [[4znw|4znw]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4znh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4znh OCA], [http://pdbe.org/4znh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4znh RCSB], [http://www.ebi.ac.uk/pdbsum/4znh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4znh ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4znh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4znh OCA], [http://pdbe.org/4znh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4znh RCSB], [http://www.ebi.ac.uk/pdbsum/4znh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4znh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4znh" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4znh" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Estrogen receptor 3D structures|Estrogen receptor 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Carlson, K E]] | [[Category: Carlson, K E]] | ||
[[Category: Cavett, V]] | [[Category: Cavett, V]] | ||