5f91: Difference between revisions

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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f92|5f92]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f92|5f92]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fumarate_hydratase Fumarate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.2 4.2.1.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fumarate_hydratase Fumarate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.2 4.2.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f91 OCA], [http://pdbe.org/5f91 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f91 RCSB], [http://www.ebi.ac.uk/pdbsum/5f91 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f91 OCA], [http://pdbe.org/5f91 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f91 RCSB], [http://www.ebi.ac.uk/pdbsum/5f91 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5f91 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 05:25, 13 July 2016

Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator (N-(5-(azepan-1-ylsulfonyl)-2-methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide)Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator (N-(5-(azepan-1-ylsulfonyl)-2-methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide)

Structural highlights

5f91 is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Activity:Fumarate hydratase, with EC number 4.2.1.2
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[FUMC_MYCTO] Catalyzes the reversible addition of water to fumarate to give L-malate.

5f91, resolution 2.00Å

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