5l4t: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of FimH lectin domain in complex with 2-Deoxy-Heptylmannoside== | |||
<StructureSection load='5l4t' size='340' side='right' caption='[[5l4t]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5l4t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L4T FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6LS:2-Deoxy-Heptylmannoside'>6LS</scene></td></tr> | |||
[[Category: | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fimH, b4320, JW4283 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), fimH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l4t OCA], [http://pdbe.org/5l4t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l4t RCSB], [http://www.ebi.ac.uk/pdbsum/5l4t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l4t ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Ecoli]] | |||
[[Category: Ernst, B]] | |||
[[Category: Jakob, R P]] | |||
[[Category: Maier, T]] | |||
[[Category: Rabbani, S]] | |||
[[Category: Zihlmann, P]] | |||
[[Category: Carbohydrate]] | |||
[[Category: Cell adhesion]] | |||
[[Category: Fimh]] | |||
[[Category: Lectin]] | |||
[[Category: Mannose]] | |||
[[Category: Sugar binding protein]] | |||
[[Category: Type 1 pilus]] | |||
[[Category: Urinary tract infection]] | |||
[[Category: Uti]] | |||
Revision as of 11:38, 16 November 2017
Crystal structure of FimH lectin domain in complex with 2-Deoxy-HeptylmannosideCrystal structure of FimH lectin domain in complex with 2-Deoxy-Heptylmannoside
Structural highlights
Function[FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. |
| ||||||||||||||||||