Nucleoporin: Difference between revisions

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{{STRUCTURE_1xip|  PDB=1xip  | SIZE=300| SCENE=Nucleoporin/Cv/1 |right|CAPTION=yeast Nucleoporin NUP159, [[1xip]] }}
{{STRUCTURE_1xip|  PDB=1xip  | SIZE=300| SCENE=Nucleoporin/Cv/1 |right|CAPTION=yeast Nucleoporin NUP159, [[1xip]] }}
[[Nucleoporin|Nucleoporins]] (NUP) are constituents of the nuclear pore complex which regulates the flow of macromolecules across the nuclear envelope.  They are named according to their molecular weights. They contain a domain which binds the protein RAN (RANBD), N-terminal domain (NTD) and C-terminal domain (CTD)<ref>PMID:9159086</ref>.  
[[Nucleoporin|Nucleoporins]] (NUP) are constituents of the nuclear pore complex which regulates the flow of macromolecules across the nuclear envelope.  They are named according to their molecular weights. They contain a domain which binds the protein RAN (RANBD), N-terminal domain (NTD) and C-terminal domain (CTD)<ref>PMID:9159086</ref>. <br />
*NUP1P is a yeast nucleoprotein required for nuclear protein import, mRNA export and maintenance of nuclear architecture<ref>PMID:8045927</ref>. <br />
*NUP2P is a yeast nucleoprotein required for bidirectional transport of importin α<ref>PMID:11046143</ref>. <br />


== 3D Structures of Nucleoporin ==
== 3D Structures of Nucleoporin ==

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Alexander Berchansky, Michal Harel, Jaime Prilusky, Joel L. Sussman