1ixg: Difference between revisions

Revision as of 20:32, 2 May 2008

PHOSPHATE-BINDING PROTEIN MUTANT WITH THR 141 REPLACED BY ASP (T141D), COMPLEXED WITH PHOSPATE

OverviewOverview

A very short hydrogen bond between an Asp and a phosphate is established in two high resolution structures (0.98 and 1.05 A). A mutant complex that changes the Asp to an Asn, which forms a normal hydrogen bond, has a similar free energy of binding to the wild type complex, suggesting that the contribution of the short hydrogen bond is not extraordinarily strong.

About this StructureAbout this Structure

1IXG is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

ReferenceReference

A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes., Wang Z, Luecke H, Yao N, Quiocho FA, Nat Struct Biol. 1997 Jul;4(7):519-22. PMID:9228942 Page seeded by OCA on Fri May 2 20:32:40 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
 [[Image:1ixg.gif|left|200px]]
- {{Structure
+<!--
-|PDB= 1ixg |SIZE=350|CAPTION= <scene name='initialview01'>1ixg</scene>, resolution 1.05&Aring;
+The line below this paragraph, containing "STRUCTURE_1ixg", creates the "Structure Box" on the page.
-|SITE=
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
-|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-|ACTIVITY=
+or leave the SCENE parameter empty for the default display.
-|GENE= PHO-S ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+-->
-|DOMAIN=
+{{STRUCTURE_1ixg|  PDB=1ixg  |  SCENE=  }}
-|RELATEDENTRY=
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ixg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ixg OCA], [http://www.ebi.ac.uk/pdbsum/1ixg PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ixg RCSB]</span>
-}}
 '''PHOSPHATE-BINDING PROTEIN MUTANT WITH THR 141 REPLACED BY ASP (T141D), COMPLEXED WITH PHOSPATE'''
@@ Line 28: / Line 25: @@
 [[Category: Quiocho, F A.]]
 [[Category: Wang, Z.]]
-[[Category: phosphate bindin protein]]
+[[Category: Phosphate bindin protein]]
-[[Category: phosphate transport]]
+[[Category: Phosphate transport]]
-[[Category: ultra high resolution]]
+[[Category: Ultra high resolution]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 20:32:40 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:26:01 2008''