5j7c: Difference between revisions

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'''Unreleased structure'''


The entry 5j7c is ON HOLD until Paper Publication
==A picomolar affinity FN3 domain in complex with hen egg-white lysozyme==
 
<StructureSection load='5j7c' size='340' side='right' caption='[[5j7c]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5j7c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J7C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5J7C FirstGlance]. <br>
Description:  
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5j7k|5j7k]]</td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5j7c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j7c OCA], [http://pdbe.org/5j7c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j7c RCSB], [http://www.ebi.ac.uk/pdbsum/5j7c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j7c ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Lysozyme]]
[[Category: Buckle, A M]]
[[Category: Drinkwater, N]]
[[Category: McGowan, S]]
[[Category: Porebski, B T]]
[[Category: Fibronectin type iii]]
[[Category: Fn3]]
[[Category: High affinity]]
[[Category: Protein binding-hydrolase complex]]
[[Category: Yeast surface display]]

Revision as of 03:05, 10 September 2016

A picomolar affinity FN3 domain in complex with hen egg-white lysozymeA picomolar affinity FN3 domain in complex with hen egg-white lysozyme

Structural highlights

5j7c is a 4 chain structure with sequence from [1] and Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Activity:Lysozyme, with EC number 3.2.1.17
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]

References

  1. ↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021

5j7c, resolution 2.54Å

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OCA
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