5ipc: Difference between revisions

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'''Unreleased structure'''


The entry 5ipc is ON HOLD  until Paper Publication
==Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) H112N mutant nucleoside thiophosphoramidate substrate complex==
 
<StructureSection load='5ipc' size='340' side='right' caption='[[5ipc]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5ipc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IPC FirstGlance]. <br>
Description:  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6CE:5-S-[(S)-HYDROXY{[2-(1H-INDOL-3-YL)ETHYL]AMINO}PHOSPHORYL]-5-THIOGUANOSINE'>6CE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tw2|3tw2]], [[5i2e|5i2e]], [[5i2f|5i2f]], [[4eqe|4eqe]], [[4eqg|4eqg]], [[4eqh|4eqh]], [[1kpa|1kpa]], [[5ipb|5ipb]], [[5ipd|5ipd]], [[5ipe|5ipe]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ipc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ipc OCA], [http://pdbe.org/5ipc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ipc RCSB], [http://www.ebi.ac.uk/pdbsum/5ipc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ipc ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/HINT1_HUMAN HINT1_HUMAN]] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity).
__TOC__
</StructureSection>
[[Category: Finzel, B C]]
[[Category: Maize, K M]]
[[Category: Hint]]
[[Category: Histidine triad]]
[[Category: Hit]]
[[Category: Hydrolase]]

Revision as of 00:18, 16 March 2017

Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) H112N mutant nucleoside thiophosphoramidate substrate complexHuman Histidine Triad Nucleotide Binding Protein 1 (hHint1) H112N mutant nucleoside thiophosphoramidate substrate complex

Structural highlights

5ipc is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[HINT1_HUMAN] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity).

5ipc, resolution 1.30Å

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OCA
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