5f91: Difference between revisions

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-'''Unreleased structure'''
-The entry 5f91 is ON HOLD  until Paper Publication
+==Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator (N-(5-(azepan-1-ylsulfonyl)-2-methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide)==
+<StructureSection load='5f91' size='340' side='right' caption='[[5f91]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5f91]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F91 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F91 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5WJ:~{N}-[5-(AZEPAN-1-YLSULFONYL)-2-METHOXY-PHENYL]-2-(4-OXIDANYLIDENE-3~{H}-PHTHALAZIN-1-YL)ETHANAMIDE'>5WJ</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f92|5f92]]</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fumarate_hydratase Fumarate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.2 4.2.1.2] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f91 OCA], [http://pdbe.org/5f91 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f91 RCSB], [http://www.ebi.ac.uk/pdbsum/5f91 PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/FUMC_MYCTO FUMC_MYCTO]] Catalyzes the reversible addition of water to fumarate to give L-malate.
+__TOC__
+</StructureSection>
+[[Category: Fumarate hydratase]]
+[[Category: Abell, C]]
+[[Category: Barry, C E]]
+[[Category: Boshoff, H I]]
+[[Category: Fischer, G]]
+[[Category: Hyvonen, M]]
+[[Category: Kasbekar, M]]
+[[Category: Mott, B T]]
+[[Category: Thomas, C J]]
+[[Category: Yasgar, A]]
+[[Category: Allostery]]
+[[Category: Hydratase]]
+[[Category: Inhibitor]]
+[[Category: Lyase-lyase inhibitor complex]]
+[[Category: Metabolism]]
+[[Category: Modulation]]
+[[Category: Tuberculosis]]