Transfer RNA tour: Difference between revisions

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===Domains===
===Domains===
[[Image:JnTphe.GIF]]
[[Image:JnTphe.GIF]]
Click here to color the tRNA 3D structure to match the secondary structure above.
<scene name='72/725890/Trna_tertcolor/3'>Color the tRNA 3D structure to match the secondary structure above</scene>.


The <B><FONT COLOR="#0000ff">acceptor stem</FONT></B> includes the 5' and 3' ends of the tRNA. The 5' end is generated by RNaseP :-). The 3' end is the site which is charged with amino acids for translation. Some aminoacyl tRNA synthetases interact with both the <B><FONT COLOR="#0000ff">acceptor</FONT></B> 3' end and
The <B><FONT COLOR="#0000ff">acceptor stem</FONT></B> includes the 5' and 3' ends of the tRNA. The 5' end is generated by RNaseP :-). The 3' end is the site which is charged with amino acids for translation. Some aminoacyl tRNA synthetases interact with both the <B><FONT COLOR="#0000ff">acceptor</FONT></B> 3' end and
the <B><FONT COLOR="#ff0000">anticodon</FONT></B> when charging tRNAs. Note how far the 3' end is from the <B><FONT COLOR="#ff0000">anticodon loop</FONT></B>, at bottom, by clicking here. Note also how the <B><FONT COLOR="#0000ff">acceptor stem</FONT></B> stacks onto the <B><FONT COLOR="#008aff">TpsiC stem</FONT></B> to form a continuous helix. The <B><FONT COLOR="#ff0000">anticodon stem</FONT></B> also stacks onto the junction between the <B><FONT COLOR="#aaaa00">variable loop</FONT></B> and the <B><FONT COLOR="#ff00ff">D stem</FONT></B> to form another nearly perfect helix. The <B><FONT COLOR="#008aff">TpsiC</FONT></B> and <B><FONT COLOR="#ff00ff">D loops</FONT></B> interact to bring the &quot;cloverleaf&quot; secondary structure in to the L-shaped tertiary structure.
the <B><FONT COLOR="#ff0000">anticodon</FONT></B> when charging tRNAs. Note how far the 3' end is from the <B><FONT COLOR="#ff0000">anticodon loop</FONT></B>, at bottom, by clicking here. Note also how the <B><FONT COLOR="#0000ff">acceptor stem</FONT></B> stacks onto the <B><FONT COLOR="#008aff">TpsiC stem</FONT></B> to form a continuous helix. The <B><FONT COLOR="#ff0000">anticodon stem</FONT></B> also stacks onto the junction between the <B><FONT COLOR="#aaaa00">variable loop</FONT></B> and the <B><FONT COLOR="#ff00ff">D stem</FONT></B> to form another nearly perfect helix. The <B><FONT COLOR="#008aff">TpsiC</FONT></B> and <B><FONT COLOR="#ff00ff">D loops</FONT></B> interact to bring the &quot;cloverleaf&quot; secondary structure in to the L-shaped tertiary structure.


 
<scene name='72/725890/Trna_tert_interact/1'>TextToBeDisplayed</scene>
The tour starts with the <scene name='72/725869/A-rna_overview/1'>Default</scene> view. Now look at this <scene name='72/725869/Rna_space_filling_view/2'>space filling view</scene>.The backbone is yellow and the bases are magenta. Note that the major groove (at the top, when you have just clicked the button) is very deep.
The tour starts with the <scene name='72/725869/A-rna_overview/1'>Default</scene> view. Now look at this <scene name='72/725869/Rna_space_filling_view/2'>space filling view</scene>.The backbone is yellow and the bases are magenta. Note that the major groove (at the top, when you have just clicked the button) is very deep.


Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

James Nolan, Michal Harel