2k17: Difference between revisions
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==Solution structure of the TAF3 PHD domain in complex with a H3K4me3 peptide== | ==Solution structure of the TAF3 PHD domain in complex with a H3K4me3 peptide== | ||
<StructureSection load='2k17' size='340' side='right' caption='[[2k17]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2k17' size='340' side='right' caption='[[2k17]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2k16|2k16]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2k16|2k16]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Taf3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Taf3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k17 OCA], [http://pdbe.org/2k17 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k17 RCSB], [http://www.ebi.ac.uk/pdbsum/2k17 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k17 OCA], [http://pdbe.org/2k17 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k17 RCSB], [http://www.ebi.ac.uk/pdbsum/2k17 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2k17 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/2k17_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/2k17_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Timmers, M]] | [[Category: Timmers, M]] | ||
[[Category: Wienk, H]] | [[Category: Wienk, H]] | ||
[[Category: Alternative splicing]] | |||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
[[Category: Nucleus]] | [[Category: Nucleus]] | ||
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[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
[[Category: Zinc]] | |||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 13:41, 18 July 2018
Solution structure of the TAF3 PHD domain in complex with a H3K4me3 peptideSolution structure of the TAF3 PHD domain in complex with a H3K4me3 peptide
Structural highlights
Function[TAF3_MOUSE] Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.[1] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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