2zu7: Difference between revisions

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==Crystal structure of mannosyl-3-phosphoglycerate synthase from Pyrococcus horikoshii==
==Crystal structure of mannosyl-3-phosphoglycerate synthase from Pyrococcus horikoshii==
<StructureSection load='2zu7' size='340' side='right' caption='[[2zu7]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2zu7' size='340' side='right' caption='[[2zu7]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PH0927 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 'Pyrococcus shinkaii'])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PH0927 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 'Pyrococcus shinkaii'])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-3-phosphoglycerate_synthase Mannosyl-3-phosphoglycerate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.217 2.4.1.217] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-3-phosphoglycerate_synthase Mannosyl-3-phosphoglycerate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.217 2.4.1.217] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zu7 OCA], [http://pdbe.org/2zu7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zu7 RCSB], [http://www.ebi.ac.uk/pdbsum/2zu7 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zu7 OCA], [http://pdbe.org/2zu7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zu7 RCSB], [http://www.ebi.ac.uk/pdbsum/2zu7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zu7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/2zu7_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/2zu7_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Tanaka, I]]
[[Category: Tanaka, I]]
[[Category: Watanabe, N]]
[[Category: Watanabe, N]]
[[Category: Cytoplasm]]
[[Category: Glycosyltransferase]]
[[Category: Glycosyltransferase]]
[[Category: Gt-a fold]]
[[Category: Gt-a fold]]

Revision as of 10:09, 18 October 2018

Crystal structure of mannosyl-3-phosphoglycerate synthase from Pyrococcus horikoshiiCrystal structure of mannosyl-3-phosphoglycerate synthase from Pyrococcus horikoshii

Structural highlights

2zu7 is a 2 chain structure with sequence from 'pyrococcus shinkaii'. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
NonStd Res:
Gene:PH0927 ('Pyrococcus shinkaii')
Activity:Mannosyl-3-phosphoglycerate synthase, with EC number 2.4.1.217
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[MPGS_PYRHO] Transfers a mannosyl group from GDP-mannose to phosphoglycerate to form mannosyl-3-phosphoglycerate (MPG). The enzyme is absolutely specific for GDP-mannose and 3-phosphoglycerate, and transfers the mannosyl group with retention of configuration.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2zu7, resolution 2.50Å

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OCA