3eb1: Difference between revisions
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==Crystal structure PTP1B complex with small molecule inhibitor LZP-25== | ==Crystal structure PTP1B complex with small molecule inhibitor LZP-25== | ||
<StructureSection load='3eb1' size='340' side='right' caption='[[3eb1]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='3eb1' size='340' side='right' caption='[[3eb1]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPN1, PTP1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPN1, PTP1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eb1 OCA], [http://pdbe.org/3eb1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3eb1 RCSB], [http://www.ebi.ac.uk/pdbsum/3eb1 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eb1 OCA], [http://pdbe.org/3eb1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3eb1 RCSB], [http://www.ebi.ac.uk/pdbsum/3eb1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3eb1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3eb1_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3eb1_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 3eb1" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3eb1" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Zhang, Z Y]] | [[Category: Zhang, Z Y]] | ||
[[Category: Zheng, L F]] | [[Category: Zheng, L F]] | ||
[[Category: Acetylation]] | |||
[[Category: Endoplasmic reticulum]] | [[Category: Endoplasmic reticulum]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
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[[Category: Oxidation]] | [[Category: Oxidation]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Polymorphism]] | |||
[[Category: Protein phosphatase]] | [[Category: Protein phosphatase]] | ||
[[Category: Protein tyrosine phosphatase]] | [[Category: Protein tyrosine phosphatase]] | ||
[[Category: Ptp1b]] | [[Category: Ptp1b]] | ||