3b84: Difference between revisions

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==Crystal structure of the human BTB domain of the Krueppel related Zinc Finger Protein 3 (HKR3)==
==Crystal structure of the human BTB domain of the Krueppel related Zinc Finger Protein 3 (HKR3)==
<StructureSection load='3b84' size='340' side='right' caption='[[3b84]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
<StructureSection load='3b84' size='340' side='right' caption='[[3b84]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZBTB48, HKR3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZBTB48, HKR3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b84 OCA], [http://pdbe.org/3b84 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3b84 RCSB], [http://www.ebi.ac.uk/pdbsum/3b84 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b84 OCA], [http://pdbe.org/3b84 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3b84 RCSB], [http://www.ebi.ac.uk/pdbsum/3b84 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3b84 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 10:57, 25 October 2017

Crystal structure of the human BTB domain of the Krueppel related Zinc Finger Protein 3 (HKR3)Crystal structure of the human BTB domain of the Krueppel related Zinc Finger Protein 3 (HKR3)

Structural highlights

3b84 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:ZBTB48, HKR3 (HUMAN)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[ZBT48_HUMAN] Binds to and regulates the J and/or S elements in MHC II promoter.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Sugawara M, Scholl T, Ponath PD, Strominger JL. A factor that regulates the class II major histocompatibility complex gene DPA is a member of a subfamily of zinc finger proteins that includes a Drosophila developmental control protein. Mol Cell Biol. 1994 Dec;14(12):8438-50. PMID:7969177

3b84, resolution 1.74Å

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OCA
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