1vdl: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Solution Structure of RSGI RUH-013, a UBA domain in Mouse cDNA== | ==Solution Structure of RSGI RUH-013, a UBA domain in Mouse cDNA== | ||
<StructureSection load='1vdl' size='340' side='right' caption='[[1vdl]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1vdl' size='340' side='right' caption='[[1vdl]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
| Line 5: | Line 6: | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 2610101O11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 2610101O11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitin_thiolesterase Ubiquitin thiolesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.2.15 3.1.2.15] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitin_thiolesterase Ubiquitin thiolesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.2.15 3.1.2.15] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vdl OCA], [http://pdbe.org/1vdl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vdl RCSB], [http://www.ebi.ac.uk/pdbsum/1vdl PDBsum], [http://www.topsan.org/Proteins/RSGI/1vdl TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vdl OCA], [http://pdbe.org/1vdl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vdl RCSB], [http://www.ebi.ac.uk/pdbsum/1vdl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vdl ProSAT], [http://www.topsan.org/Proteins/RSGI/1vdl TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| Line 13: | Line 14: | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vd/1vdl_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vd/1vdl_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
Revision as of 10:46, 4 April 2018
Solution Structure of RSGI RUH-013, a UBA domain in Mouse cDNASolution Structure of RSGI RUH-013, a UBA domain in Mouse cDNA
Structural highlights
Function[UBP25_MOUSE] Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains (By similarity).[1] The muscle-specific isoform (USP25m) may have a role in the regulation of muscular differentiation and function.[2] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
|
| ||||||||||||||||||