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==A STRUCTURAL BASIS FOR THE CHIRAL PREFERENCES OF LIPASES==
==A STRUCTURAL BASIS FOR THE CHIRAL PREFERENCES OF LIPASES==
<StructureSection load='1lpm' size='340' side='right' caption='[[1lpm]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
<StructureSection load='1lpm' size='340' side='right' caption='[[1lpm]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPA:(1R)-MENTHYL+HEXYL+PHOSPHONATE+GROUP'>MPA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPA:(1R)-MENTHYL+HEXYL+PHOSPHONATE+GROUP'>MPA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lpm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lpm OCA], [http://pdbe.org/1lpm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1lpm RCSB], [http://www.ebi.ac.uk/pdbsum/1lpm PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lpm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lpm OCA], [http://pdbe.org/1lpm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1lpm RCSB], [http://www.ebi.ac.uk/pdbsum/1lpm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1lpm ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lp/1lpm_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lp/1lpm_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Lipase|Lipase]]
*[[Lipase lid morph|Lipase lid morph]]
*[[Lipase lid morph|Lipase lid morph]]
*[[Practical Guide to Homology Modeling|Practical Guide to Homology Modeling]]
*[[Practical Guide to Homology Modeling|Practical Guide to Homology Modeling]]

Revision as of 10:45, 31 January 2018

A STRUCTURAL BASIS FOR THE CHIRAL PREFERENCES OF LIPASESA STRUCTURAL BASIS FOR THE CHIRAL PREFERENCES OF LIPASES

Structural highlights

1lpm is a 1 chain structure with sequence from Atcc 10571. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Activity:Triacylglycerol lipase, with EC number 3.1.1.3
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1lpm, resolution 2.18Å

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