1w5y: Difference between revisions
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==HIV-1 | |||
==HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor== | |||
<StructureSection load='1w5y' size='340' side='right' caption='[[1w5y]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='1w5y' size='340' side='right' caption='[[1w5y]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ajv|1ajv]], [[1ajx|1ajx]], [[1axa|1axa]], [[1bqm|1bqm]], [[1bqn|1bqn]], [[1d4h|1d4h]], [[1d4i|1d4i]], [[1d4j|1d4j]], [[1dlo|1dlo]], [[1dw6|1dw6]], [[1ebk|1ebk]], [[1ebw|1ebw]], [[1eby|1eby]], [[1ebz|1ebz]], [[1ec0|1ec0]], [[1ec1|1ec1]], [[1ec2|1ec2]], [[1ec3|1ec3]], [[1eet|1eet]], [[1hbv|1hbv]], [[1hef|1hef]], [[1heg|1heg]], [[1hih|1hih]], [[1hmv|1hmv]], [[1hni|1hni]], [[1hnv|1hnv]], [[1hos|1hos]], [[1hps|1hps]], [[1hpz|1hpz]], [[1hqe|1hqe]], [[1hqu|1hqu]], [[1hrh|1hrh]], [[1hte|1hte]], [[1htf|1htf]], [[1htg|1htg]], [[1hvk|1hvk]], [[1hvp|1hvp]], [[1hvu|1hvu]], [[1hys|1hys]], [[1ikv|1ikv]], [[1ikw|1ikw]], [[1ikx|1ikx]], [[1iky|1iky]], [[1j5o|1j5o]], [[1mer|1mer]], [[1mes|1mes]], [[1met|1met]], [[1meu|1meu]], [[1n5y|1n5y]], [[1n6q|1n6q]], [[1qe1|1qe1]], [[1qmc|1qmc]], [[1r0a|1r0a]], [[1rdh|1rdh]], [[1rtd|1rtd]], [[1rvl|1rvl]], [[1rvm|1rvm]], [[1rvn|1rvn]], [[1rvo|1rvo]], [[1rvp|1rvp]], [[1rvq|1rvq]], [[1rvr|1rvr]], [[1s6p|1s6p]], [[1s6q|1s6q]], [[1s9e|1s9e]], [[1s9g|1s9g]], [[1sbg|1sbg]], [[1suq|1suq]], [[1sv5|1sv5]], [[1t03|1t03]], [[1t05|1t05]], [[1tv6|1tv6]], [[1tvr|1tvr]], [[1uwb|1uwb]], [[1w5v|1w5v]], [[1w5w|1w5w]], [[1w5x|1w5x]], [[2hmi|2hmi]], [[3hvt|3hvt]], [[3tlh|3tlh]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ajv|1ajv]], [[1ajx|1ajx]], [[1axa|1axa]], [[1bqm|1bqm]], [[1bqn|1bqn]], [[1d4h|1d4h]], [[1d4i|1d4i]], [[1d4j|1d4j]], [[1dlo|1dlo]], [[1dw6|1dw6]], [[1ebk|1ebk]], [[1ebw|1ebw]], [[1eby|1eby]], [[1ebz|1ebz]], [[1ec0|1ec0]], [[1ec1|1ec1]], [[1ec2|1ec2]], [[1ec3|1ec3]], [[1eet|1eet]], [[1hbv|1hbv]], [[1hef|1hef]], [[1heg|1heg]], [[1hih|1hih]], [[1hmv|1hmv]], [[1hni|1hni]], [[1hnv|1hnv]], [[1hos|1hos]], [[1hps|1hps]], [[1hpz|1hpz]], [[1hqe|1hqe]], [[1hqu|1hqu]], [[1hrh|1hrh]], [[1hte|1hte]], [[1htf|1htf]], [[1htg|1htg]], [[1hvk|1hvk]], [[1hvp|1hvp]], [[1hvu|1hvu]], [[1hys|1hys]], [[1ikv|1ikv]], [[1ikw|1ikw]], [[1ikx|1ikx]], [[1iky|1iky]], [[1j5o|1j5o]], [[1mer|1mer]], [[1mes|1mes]], [[1met|1met]], [[1meu|1meu]], [[1n5y|1n5y]], [[1n6q|1n6q]], [[1qe1|1qe1]], [[1qmc|1qmc]], [[1r0a|1r0a]], [[1rdh|1rdh]], [[1rtd|1rtd]], [[1rvl|1rvl]], [[1rvm|1rvm]], [[1rvn|1rvn]], [[1rvo|1rvo]], [[1rvp|1rvp]], [[1rvq|1rvq]], [[1rvr|1rvr]], [[1s6p|1s6p]], [[1s6q|1s6q]], [[1s9e|1s9e]], [[1s9g|1s9g]], [[1sbg|1sbg]], [[1suq|1suq]], [[1sv5|1sv5]], [[1t03|1t03]], [[1t05|1t05]], [[1tv6|1tv6]], [[1tvr|1tvr]], [[1uwb|1uwb]], [[1w5v|1w5v]], [[1w5w|1w5w]], [[1w5x|1w5x]], [[2hmi|2hmi]], [[3hvt|3hvt]], [[3tlh|3tlh]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5y OCA], [http://pdbe.org/1w5y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w5y RCSB], [http://www.ebi.ac.uk/pdbsum/1w5y PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5y OCA], [http://pdbe.org/1w5y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w5y RCSB], [http://www.ebi.ac.uk/pdbsum/1w5y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1w5y ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/1w5y_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/1w5y_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 1w5y" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1w5y" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||