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==Iodine derivative of hen egg-white lysozyme== | ==Iodine derivative of hen egg-white lysozyme== | ||
<StructureSection load='1vat' size='340' side='right' caption='[[1vat]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='1vat' size='340' side='right' caption='[[1vat]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1vat]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1vat]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VAT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VAT FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vau|1vau]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vau|1vau]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vat OCA], [http://pdbe.org/1vat PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vat RCSB], [http://www.ebi.ac.uk/pdbsum/1vat PDBsum], [http://www.topsan.org/Proteins/RSGI/1vat TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vat FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vat OCA], [http://pdbe.org/1vat PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vat RCSB], [http://www.ebi.ac.uk/pdbsum/1vat PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vat ProSAT], [http://www.topsan.org/Proteins/RSGI/1vat TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| Line 14: | Line 15: | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/va/1vat_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/va/1vat_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 27: | Line 28: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Gallus gallus]] | ||
[[Category: Lysozyme]] | [[Category: Lysozyme]] | ||
[[Category: Kamiya, N]] | [[Category: Kamiya, N]] | ||
| Line 34: | Line 35: | ||
[[Category: Miyatake, H]] | [[Category: Miyatake, H]] | ||
[[Category: Park, S Y]] | [[Category: Park, S Y]] | ||
[[Category: Structural genomic]] | |||
[[Category: Takeda, K]] | [[Category: Takeda, K]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Iodine-derivative]] | [[Category: Iodine-derivative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
Revision as of 10:13, 4 April 2018
Iodine derivative of hen egg-white lysozymeIodine derivative of hen egg-white lysozyme
Structural highlights
Function[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
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