2ja2: Difference between revisions

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==MYCOBACTERIUM TUBERCULOSIS GLUTAMYL-TRNA SYNTHETASE==
 
==Mycobacterium tuberculosis glutamyl-tRNA synthetase==
<StructureSection load='2ja2' size='340' side='right' caption='[[2ja2]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='2ja2' size='340' side='right' caption='[[2ja2]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate--tRNA_ligase Glutamate--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.17 6.1.1.17] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate--tRNA_ligase Glutamate--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.17 6.1.1.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ja2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ja2 OCA], [http://pdbe.org/2ja2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ja2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ja2 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ja2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ja2 OCA], [http://pdbe.org/2ja2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ja2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ja2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ja2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/2ja2_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/2ja2_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>

Revision as of 10:14, 11 July 2018

Mycobacterium tuberculosis glutamyl-tRNA synthetaseMycobacterium tuberculosis glutamyl-tRNA synthetase

Structural highlights

2ja2 is a 1 chain structure with sequence from Myctu. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:Glutamate--tRNA ligase, with EC number 6.1.1.17
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[SYE_MYCTU] Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2ja2, resolution 1.65Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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