DNA polymerase: Difference between revisions
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<StructureSection load='1taq' size='350' side='right' scene='' caption='Family A DNA polymerase I complex with octylglucoside [[1taq]]'> | <StructureSection load='1taq' size='350' side='right' scene='44/440019/Cv/2' caption='Family A DNA polymerase I complex with octylglucoside [[1taq]]'> | ||
[[DNA polymerase]] '''(Dpo)''' reads a [[DNA|DNA strand]] and catalyzes the synthesis of its complementary strand. Dpo's are divided into 7 families according to their sequence homology and 3D structure similarities.<ref>PMID:10364165</ref> The families are:<br /> | [[DNA polymerase]] '''(Dpo)''' reads a [[DNA|DNA strand]] and catalyzes the synthesis of its complementary strand. Dpo's are divided into 7 families according to their sequence homology and 3D structure similarities.<ref>PMID:10364165</ref> The families are:<br /> | ||
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* '''Rev1''' is a '''Dpo''' involved in replication over DNA lesions. <br /> | * '''Rev1''' is a '''Dpo''' involved in replication over DNA lesions. <br /> | ||
* '''Terminal deoxynucleotidyl transferase (TdT)''' is a family X Dpo expressed in immature lymphoid cells. TdT adds nucleotides to exons during antibody gene recombination.<br /> | * '''Terminal deoxynucleotidyl transferase (TdT)''' is a family X Dpo expressed in immature lymphoid cells. TdT adds nucleotides to exons during antibody gene recombination.<br /> | ||
<scene name='44/440019/Cv/4'>Octylglucoside binding site</scene> in Family A DNA polymerase I ([[1taq]]). | |||
See also [[User:Karl E. Zahn/RB69 DNA polymerase (gp43)]]<br /> | See also [[User:Karl E. Zahn/RB69 DNA polymerase (gp43)]]<br /> | ||
</StructureSection> | </StructureSection> | ||