4wrc: Difference between revisions

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-'''Unreleased structure'''
+==Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D)==
+<StructureSection load='4wrc' size='340' side='right' caption='[[4wrc]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-The entry 4wrc is ON HOLD  until Feb 10 2017
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4wrc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WRC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WRC FirstGlance]. <br>
-Authors: Rynkiewicz, M.J., Wu, H., Cafarella, T.R., Nikolaidis, N.M., Head, J.F., Seaton, B.A., McCormack, F.X.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wre|4wre]], [[4wrf|4wrf]], [[4wr9|4wr9]]</td></tr>
-Description: Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D)
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wrc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wrc OCA], [http://pdbe.org/4wrc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wrc RCSB], [http://www.ebi.ac.uk/pdbsum/4wrc PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Head, J.F]]
+== Function ==
-[[Category: Seaton, B.A]]
+[[http://www.uniprot.org/uniprot/SFTPA_RAT SFTPA_RAT]] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
-[[Category: Mccormack, F.X]]
+__TOC__
-[[Category: Cafarella, T.R]]
+</StructureSection>
-[[Category: Nikolaidis, N.M]]
+[[Category: Cafarella, T R]]
+[[Category: Head, J F]]
+[[Category: McCormack, F X]]
+[[Category: Nikolaidis, N M]]
+[[Category: Rynkiewicz, M J]]
+[[Category: Seaton, B A]]
 [[Category: Wu, H]]
-[[Category: Rynkiewicz, M.J]]
+[[Category: Carbohydrate binding]]
+[[Category: Collectin]]
+[[Category: Lectin]]
+[[Category: Lipid binding]]
+[[Category: Sugar binding protein]]