5ft9: Difference between revisions

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-'''Unreleased structure'''
+==Arabidopsis thaliana nuclear protein-only RNase P 2 (PRORP2)==
+<StructureSection load='5ft9' size='340' side='right' caption='[[5ft9]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5ft9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FT9 FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_P Ribonuclease P], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.5 3.1.26.5] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ft9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ft9 OCA], [http://pdbe.org/5ft9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ft9 RCSB], [http://www.ebi.ac.uk/pdbsum/5ft9 PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/PRRP2_ARATH PRRP2_ARATH]] Endonuclease RNase P responsible for the 5' maturation of tRNA precursors. Also involved in the maturation of mRNA and small nucleolar RNA (snoRNA).<ref>PMID:22549728</ref>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+RNase P activity is ubiquitous and involves the 5' maturation of precursor tRNAs. For a long time, it was thought that all RNases P were ribonucleoproteic enzymes. However, the characterization of RNase P in human mitochondria and in plants revealed a novel kind of RNase P composed of protein only, called PRORP for `proteinaceous RNase P'. Whereas in human mitochondria PRORP has two partners that are required for RNase P activity, PRORP proteins are active as single-subunit enzymes in plants. Three paralogues of PRORP are found in Arabidopsis thaliana. PRORP1 is responsible for RNase P in mitochondria and chloroplasts, while PRORP2 and PRORP3 are nuclear enzymes. Here, the purification and crystallization of the Arabidopsis PRORP2 protein are reported. Optimization of the initial crystallization conditions led to crystals that diffracted to 3 A resolution.
-The entry 5ft9 is ON HOLD
+Crystallization and crystallographic analysis of an Arabidopsis nuclear proteinaceous RNase P.,Pinker F, Giege P, Sauter C Acta Crystallogr F Struct Biol Commun. 2015 Nov 1;71(Pt 11):1372-7. doi:, 10.1107/S2053230X15017033. Epub 2015 Oct 23. PMID:26527263<ref>PMID:26527263</ref>
-Authors: Fernandez-Millan, P., Pinker, F., Schelcher, C., Gobert, A., Giege, P., Sauter, C.
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-Description: Arabidopsis thaliana nuclear protein-only RNase P 2 (PRORP2)
+<div class="pdbe-citations 5ft9" style="background-color:#fffaf0;"></div>
-[[Category: Unreleased Structures]]
+== References ==
-[[Category: Pinker, F]]
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Ribonuclease P]]
+[[Category: Fernandez-Millan, P]]
 [[Category: Giege, P]]
-[[Category: Schelcher, C]]
 [[Category: Gobert, A]]
-[[Category: Fernandez-Millan, P]]
+[[Category: Pinker, F]]
 [[Category: Sauter, C]]
+[[Category: Schelcher, C]]
+[[Category: Hydrolase]]
+[[Category: Ppr]]
+[[Category: Prorp]]
+[[Category: Proteinaceous rnase p]]
+[[Category: Trna 5' maturation]]