4yh3: Difference between revisions
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==Crystal structure of human BRD4(1) in complex with 4-[(2E)-3-(4-methoxyphenyl)-2-phenylprop-2-enoyl]-3,4-dihydroquinoxalin-2(1H)-one (compound 19a)== | ==Crystal structure of human BRD4(1) in complex with 4-[(2E)-3-(4-methoxyphenyl)-2-phenylprop-2-enoyl]-3,4-dihydroquinoxalin-2(1H)-one (compound 19a)== | ||
<StructureSection load='4yh3' size='340' side='right' caption='[[4yh3]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='4yh3' size='340' side='right' caption='[[4yh3]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4yh3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YH3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YH3 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4yh3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YH3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YH3 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=Y80:4-[(2E)-3-(4-METHOXYPHENYL)-2-PHENYLPROP-2-ENOYL]-3,4-DIHYDROQUINOXALIN-2(1H)-ONE'>Y80</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=Y80:4-[(2E)-3-(4-METHOXYPHENYL)-2-PHENYLPROP-2-ENOYL]-3,4-DIHYDROQUINOXALIN-2(1H)-ONE'>Y80</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yh4|4yh4]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yh4|4yh4]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yh3 OCA], [http://pdbe.org/4yh3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yh3 RCSB], [http://www.ebi.ac.uk/pdbsum/4yh3 PDBsum]</span></td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yh3 OCA], [http://pdbe.org/4yh3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yh3 RCSB], [http://www.ebi.ac.uk/pdbsum/4yh3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yh3 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Lakshminarasimhan, D]] | [[Category: Lakshminarasimhan, D]] | ||
[[Category: Suto, R K]] | [[Category: Suto, R K]] | ||
[[Category: White, A]] | [[Category: White, A]] | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||