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==Crystal structure of the R111K:Y134F:T54V:R132Q:P39Y:R59Y mutant of human Cellular Retinoic Acid Binding Protein II with Retinal - UV irradiated crystal for 30 minutes - 1st Cycle== | |||
<StructureSection load='4yfr' size='340' side='right' caption='[[4yfr]], [[Resolution|resolution]] 1.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4yfr]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YFR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YFR FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr> | |||
[[ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ybp|4ybp]], [[4ybu|4ybu]], [[4i9s|4i9s]], [[4ruu|4ruu]], [[4eej|4eej]], [[4yfp|4yfp]], [[4yfq|4yfq]]</td></tr> | ||
[[Category: Geiger, J | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yfr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yfr OCA], [http://pdbe.org/4yfr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yfr RCSB], [http://www.ebi.ac.uk/pdbsum/4yfr PDBsum]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN]] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Geiger, J H]] | |||
[[Category: Nosrati, M]] | [[Category: Nosrati, M]] | ||
[[Category: Photo switchable protein]] | |||
[[Category: Protein engineering]] | |||
[[Category: Retinal isomerization]] | |||
[[Category: Retinal protonated schiff base pka change]] | |||
[[Category: Transport protein]] | |||
Revision as of 18:18, 2 March 2016
Crystal structure of the R111K:Y134F:T54V:R132Q:P39Y:R59Y mutant of human Cellular Retinoic Acid Binding Protein II with Retinal - UV irradiated crystal for 30 minutes - 1st CycleCrystal structure of the R111K:Y134F:T54V:R132Q:P39Y:R59Y mutant of human Cellular Retinoic Acid Binding Protein II with Retinal - UV irradiated crystal for 30 minutes - 1st Cycle
Structural highlights
Function[RABP2_HUMAN] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. |
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