5fg4: Difference between revisions

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-'''Unreleased structure'''
+==Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe==
+<StructureSection load='5fg4' size='340' side='right' caption='[[5fg4]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
-The entry 5fg4 is ON HOLD
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5fg4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FG4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FG4 FirstGlance]. <br>
-Authors: Tallant, C., Owen, D.R., Gerstenberger, B.S., Savitsky, P., Chaikuad, A., Fedorov, O., Nunez-Alonso, G., Filippakopoulos, P., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Muller, S., Knapp, S.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5XE:4-BROMANYL-~{N}-(6-METHOXY-1,3-DIMETHYL-2-OXIDANYLIDENE-BENZIMIDAZOL-5-YL)-2-METHYL-BENZENESULFONAMIDE'>5XE</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fg4 OCA], [http://pdbe.org/5fg4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fg4 RCSB], [http://www.ebi.ac.uk/pdbsum/5fg4 PDBsum]</span></td></tr>
-Description: Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe
+</table>
-[[Category: Unreleased Structures]]
+== Function ==
-[[Category: Gerstenberger, B.S]]
+[[http://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Arrowsmith, C H]]
+[[Category: Bountra, C]]
 [[Category: Chaikuad, A]]
-[[Category: Owen, D.R]]
+[[Category: Delft, F von]]
-[[Category: Nunez-Alonso, G]]
+[[Category: Edwards, A M]]
 [[Category: Fedorov, O]]
+[[Category: Filippakopoulos, P]]
+[[Category: Gerstenberger, B S]]
+[[Category: Knapp, S]]
 [[Category: Muller, S]]
-[[Category: Knapp, S]]
+[[Category: Nunez-Alonso, G]]
-[[Category: Bountra, C]]
+[[Category: Owen, D R]]
-[[Category: Arrowsmith, C.H]]
+[[Category: Savitsky, P]]
-[[Category: Von Delft, F]]
-[[Category: Filippakopoulos, P]]
-[[Category: Edwards, A.M]]
 [[Category: Tallant, C]]
-[[Category: Savitsky, P]]
+[[Category: Moz-morf complex]]
+[[Category: Peregrin]]
+[[Category: Transcription]]