5do7: Difference between revisions

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-'''Unreleased structure'''
-The entry 5do7 is ON HOLD  until Paper Publication
+==Crystal Structure of the Human Sterol Transporter ABCG5/ABCG8==
+<StructureSection load='5do7' size='340' side='right' caption='[[5do7]], [[Resolution|resolution]] 3.93&Aring;' scene=''>
-Authors: Lee, J.-Y., Kinch, L.N., Borek, D.M., Urbatsch, I.L., Xie, X.-S., Grishin, N.V., Cohen, J.C., Otwinowski, Z., Hobbs, H.H., Rosenbaum, D.M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5do7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DO7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DO7 FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5do7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5do7 OCA], [http://pdbe.org/5do7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5do7 RCSB], [http://www.ebi.ac.uk/pdbsum/5do7 PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Cohen, J.C]]
+== Disease ==
-[[Category: Grishin, N.V]]
+[[http://www.uniprot.org/uniprot/ABCG5_HUMAN ABCG5_HUMAN]] Sitosterolemia. The disease is caused by mutations affecting the gene represented in this entry. [[http://www.uniprot.org/uniprot/ABCG8_HUMAN ABCG8_HUMAN]] Sitosterolemia. Disease susceptibility may be associated with variations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
-[[Category: Kinch, L.N]]
+== Function ==
-[[Category: Lee, J.-Y]]
+[[http://www.uniprot.org/uniprot/ABCG5_HUMAN ABCG5_HUMAN]] Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. [[http://www.uniprot.org/uniprot/ABCG8_HUMAN ABCG8_HUMAN]] Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.
-[[Category: Xie, X.-S]]
+__TOC__
-[[Category: Urbatsch, I.L]]
+</StructureSection>
-[[Category: Borek, D.M]]
+[[Category: Borek, D M]]
-[[Category: Rosenbaum, D.M]]
+[[Category: Cohen, J C]]
-[[Category: Hobbs, H.H]]
+[[Category: Grishin, N V]]
+[[Category: Hobbs, H H]]
+[[Category: Kinch, L N]]
+[[Category: Lee, J Y]]
 [[Category: Otwinowski, Z]]
+[[Category: Rosenbaum, D M]]
+[[Category: Urbatsch, I L]]
+[[Category: Xie, X S]]
+[[Category: Abcg]]
+[[Category: Atp-binding cassette transporter]]
+[[Category: Sitosterolemia]]
+[[Category: Sterol efflux]]
+[[Category: Transport protein]]