4x6t: Difference between revisions

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'''Unreleased structure'''
==M.tuberculosis betalactamase complexed with inhibitor EC19==
 
<StructureSection load='4x6t' size='340' side='right' caption='[[4x6t]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
The entry 4x6t is ON HOLD  until Dec 23 2016
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4x6t]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X6T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X6T FirstGlance]. <br>
Authors: Hazra, S.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3Y6:3-[(2R)-2-(DIHYDROXYBORANYL)-2-{[(2R)-2-{[(4-ETHYL-2,3-DIOXO-3,4-DIHYDROPYRAZIN-1(2H)-YL)CARBONYL]AMINO}-2-(4-HYDROXYPHENYL)ACETYL]AMINO}ETHYL]BENZOIC+ACID'>3Y6</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
 
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
Description:
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x6t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x6t OCA], [http://pdbe.org/4x6t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x6t RCSB], [http://www.ebi.ac.uk/pdbsum/4x6t PDBsum]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
__TOC__
</StructureSection>
[[Category: Beta-lactamase]]
[[Category: Hazra, S]]
[[Category: Hazra, S]]
[[Category: Beta-lactam]]
[[Category: Boronate]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Penicillin binding protein]]
[[Category: Structure based drug development]]
[[Category: Transition state inhibitor]]

Revision as of 15:46, 23 December 2015

M.tuberculosis betalactamase complexed with inhibitor EC19M.tuberculosis betalactamase complexed with inhibitor EC19

Structural highlights

4x6t is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:Beta-lactamase, with EC number 3.5.2.6
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

4x6t, resolution 1.40Å

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