Cruzain: Difference between revisions

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<StructureSection load='1me3' size='350' side='right' caption='Structure of cruzain catalytic domain complex with methylketone inhibitor (PDB entry [[1me3]])' scene=''>


<StructureSection load='1me3' size='350' side='right' caption='Structure of cruzain complex with methylketone inhibitor (PDB entry [[1me3]])' scene=''>
'''Cruzain''' (Cru) is the major cysteine protease present in ''Trypanosoma cruzi'' which is the parasite causing Chagas disease. <ref>PMID:10997902</ref>  
 
== Relevance ==
 
Cru inhibitors are being investigated for therapeutic use against Chagas disease.


'''Cruzain''' (Cru) is the major cysteine protease present in ''Trypanosoma cruzi'' which is the parasite causing Chagas disease. <ref>PMID:7707373</ref>
</StructureSection>
</StructureSection>
==3D structures of cruzain==
==3D structures of cruzain==

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Michal Harel, Alexander Berchansky