CREB-binding protein: Difference between revisions

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== Structural highlights ==
== Structural highlights ==


CBP contains several domains.  Among them the lysine recognition bromodomain; domains KIX, TAZ1 and TAZ2 which bind sequences spanning the transactivation domain of transcription factor p53;  IBiD which binds the interferon response; ZZ is a zinc-binding motif; CH1 interacts with the N-terminal of p73.
CBP contains several domains.  Among them the lysine recognition bromodomain; domains KIX, TAZ1 and TAZ2 which bind sequences spanning the transactivation domain of transcription factor p53;  IBiD which binds the interferon response; ZZ is a zinc-binding motif; CH1 (Cys- and His-rich region 1) interacts with the N-terminal of p73.


== 3D Structures of CREB-binding protein ==
== 3D Structures of CREB-binding protein ==

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Michal Harel, Alexander Berchansky