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==Gallus interleukin-1 beta mutant - E118A== | ==Gallus interleukin-1 beta mutant - E118A== | ||
<StructureSection load='4x38' size='340' side='right' caption='[[4x38]], [[Resolution|resolution]] 2.12Å' scene=''> | <StructureSection load='4x38' size='340' side='right'caption='[[4x38]], [[Resolution|resolution]] 2.12Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4x38]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X38 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X38 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4x38]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X38 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X38 FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x37|4x37]], [[4x39|4x39]], [[4x3a|4x3a]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x37|4x37]], [[4x39|4x39]], [[4x3a|4x3a]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x38 OCA], [http://pdbe.org/4x38 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x38 RCSB], [http://www.ebi.ac.uk/pdbsum/4x38 PDBsum]</span></td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">il-1beta, IL1B, IL1beta ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x38 OCA], [http://pdbe.org/4x38 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x38 RCSB], [http://www.ebi.ac.uk/pdbsum/4x38 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x38 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/O73909_CHICK O73909_CHICK]] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753] | [[http://www.uniprot.org/uniprot/O73909_CHICK O73909_CHICK]] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753] | ||
==See Also== | |||
*[[Interleukin|Interleukin]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Chick]] | |||
[[Category: Large Structures]] | |||
[[Category: Cheng, W T]] | [[Category: Cheng, W T]] | ||
[[Category: Yin, H S]] | [[Category: Yin, H S]] | ||
[[Category: Immune system]] | [[Category: Immune system]] | ||
Revision as of 10:03, 29 May 2019
Gallus interleukin-1 beta mutant - E118AGallus interleukin-1 beta mutant - E118A
Structural highlights
Function[O73909_CHICK] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753] See Also |
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