Catalase: Difference between revisions

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<StructureSection load='1gge' size='350' side='right' scene='46/467276/Cv/1' caption='E. coli catalase Hpii tetramer showing the heme group, [[1gge]]'>
<StructureSection load='1gge' size='350' side='right' scene='46/467276/Cv/1' caption='E. coli catalase Hpii tetramer showing the heme group, [[1gge]]'>


'''Catalase''' (CAT) catalyzes the conversion of hydrogen peroxide to water and oxygen.  CAT contains porphyrin-heme Fe group which reacts with the hydrogen peroxide.  CAT containing Mn are called pseudocatalase (PCAT).<ref>PMID:21524057</ref>  '''Catalase-peroxidase''' (CAT KatG) is a bifunctional enzyme with both catalase and peroxidase activities.  CAT KatG cofactor is a heme group.  It provides defense against oxidative stress by reducing hydrogen peroxide.  Mutations in CAT KatG can cause resistance to the anti-malarial drug isoniazid (INH).<ref>PMID:15231843</ref>  '''Catalase-phenol oxidase''' (CATPO) is a heme-containing CAT which shows phenol oxidase activity.<ref>PMID:22370948</ref>
'''Catalase''' (CAT) catalyzes the conversion of hydrogen peroxide to water and oxygen.  CAT contains porphyrin-heme Fe group which reacts with the hydrogen peroxide.  CAT containing Mn are called pseudocatalase (PCAT).<ref>PMID:21524057</ref> See also [[Ann Taylor/Catalase]]. '''Catalase-peroxidase''' (CAT KatG) is a bifunctional enzyme with both catalase and peroxidase activities.  CAT KatG cofactor is a heme group.  It provides defense against oxidative stress by reducing hydrogen peroxide.  Mutations in CAT KatG can cause resistance to the anti-malarial drug isoniazid (INH).<ref>PMID:15231843</ref>  '''Catalase-phenol oxidase''' (CATPO) is a heme-containing CAT which shows phenol oxidase activity.<ref>PMID:22370948</ref>




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Michal Harel, Alexander Berchansky, Ann Taylor, Karsten Theis