1aft: Difference between revisions

Revision as of 10:12, 2 May 2008

SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES

OverviewOverview

The structure of peptide N-AcYTLDADF when bound to the large subunit of mouse ribonucleotide reductase has been elucidated by transfer NOE. This structure suggests a general design for type 1 RR inhibitors.

About this StructureAbout this Structure

1AFT is a Single protein structure. Full crystallographic information is available from OCA.

ReferenceReference

NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit., Fisher A, Laub PB, Cooperman BS, Nat Struct Biol. 1995 Nov;2(11):951-5. PMID:7583667 Page seeded by OCA on Fri May 2 10:12:42 2008

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OCA

@@ Line 1: / Line 1: @@
 [[Image:1aft.gif|left|200px]]
- {{Structure
+<!--
-|PDB= 1aft |SIZE=350|CAPTION= <scene name='initialview01'>1aft</scene>
+The line below this paragraph, containing "STRUCTURE_1aft", creates the "Structure Box" on the page.
-|SITE=
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
-|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span>
+or leave the SCENE parameter empty for the default display.
-|GENE=
+-->
-|DOMAIN=
+{{STRUCTURE_1aft|  PDB=1aft  |  SCENE=  }}
-|RELATEDENTRY=
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1aft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aft OCA], [http://www.ebi.ac.uk/pdbsum/1aft PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1aft RCSB]</span>
-}}
 '''SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES'''
@@ Line 19: / Line 16: @@
 ==About this Structure==
-AFT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AFT OCA].
+AFT is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AFT OCA].
 ==Reference==
@@ Line 31: / Line 28: @@
 [[Category: Hamann, C S.]]
 [[Category: Laub, P B.]]
-[[Category: nonstandard type i turn]]
+[[Category: Nonstandard type i turn]]
-[[Category: peptide inhibitor]]
+[[Category: Peptide inhibitor]]
-[[Category: restrained molecular dynamic]]
+[[Category: Restrained molecular dynamic]]
-[[Category: ribonucleotide reductase]]
+[[Category: Ribonucleotide reductase]]
-[[Category: transferred noesy]]
+[[Category: Transferred noesy]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 10:12:42 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:39:19 2008''