4x5j: Difference between revisions

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-'''Unreleased structure'''
+==ecDHFR complexed with folate and NADP+ at 750 MPa==
+<StructureSection load='4x5j' size='340' side='right' caption='[[4x5j]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
-The entry 4x5j is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4x5j]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X5J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X5J FirstGlance]. <br>
-Authors: Yamada, H., Watanabe, N., Nagae, T.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4x5f|4x5f]], [[4x5g|4x5g]], [[4x5h|4x5h]], [[4x5i|4x5i]]</td></tr>
-Description: ecDHFR complexed with folate and NADP+ at 750 MPa
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x5j OCA], [http://pdbe.org/4x5j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x5j RCSB], [http://www.ebi.ac.uk/pdbsum/4x5j PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
+__TOC__
+</StructureSection>
+[[Category: Dihydrofolate reductase]]
+[[Category: Nagae, T]]
 [[Category: Watanabe, N]]
 [[Category: Yamada, H]]
-[[Category: Nagae, T]]
+[[Category: Oxidoreductase]]