4uez: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH==
+<StructureSection load='4uez' size='340' side='right' caption='[[4uez]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
-The entry 4uez is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4uez]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UEZ FirstGlance]. <br>
-Authors: Gallego, P., Covaleda, G., Costenaro, L., Devel, L., Dive, V., Aviles, F.X., Reverter, D.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LFF:(2S)-3-[(R)-{(1R)-1-[(N-ACETYL-L-LEUCYL)AMINO]-2-PHENYLETHYL}(HYDROXY)PHOSPHORYL]-2-BENZYLPROPANOIC+ACID'>LFF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uee|4uee]], [[4uef|4uef]], [[4uf4|4uf4]], [[5aek|5aek]]</td></tr>
-Description: Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uez OCA], [http://pdbe.org/4uez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uez RCSB], [http://www.ebi.ac.uk/pdbsum/4uez PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CBPA1_HUMAN CBPA1_HUMAN]] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.<ref>PMID:8806703</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Carboxypeptidase A]]
+[[Category: Aviles, F X]]
+[[Category: Costenaro, L]]
+[[Category: Covaleda, G]]
+[[Category: Devel, L]]
 [[Category: Dive, V]]
 [[Category: Gallego, P]]
-[[Category: Aviles, F.X]]
 [[Category: Reverter, D]]
-[[Category: Costenaro, L]]
+[[Category: Carboxypeptidase]]
-[[Category: Covaleda, G]]
+[[Category: Cpa1]]
-[[Category: Devel, L]]
+[[Category: Hydrolase]]
+[[Category: Phosphinic inhibitor]]