Catabolite control protein: Difference between revisions
No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='2fep' size='450' side='right' caption='Structure of catabolite control protein (deepskyblue) complex with Hpr (green) and sulfate (PDB entry [[2fep]])' scene='57/570565/Cv/1'> | <StructureSection load='2fep' size='450' side='right' caption='Structure of catabolite control protein (deepskyblue) complex with Hpr (green) and sulfate (PDB entry [[2fep]])' scene='57/570565/Cv/1'> | ||
== Function == | |||
'''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.<ref>PMID:16321938</ref> | '''Catabolite control protein''' (CcpA) is a regulator of carbon metabolism in gram-positive bacteria. When high concentrations of glucose-6 phosphate or fructose-1,6-diphosphate are present in the cell, they phosphorylate proteins HPr or Crh which interact with CcpA. The latter binds to DNA operator to modulate transcription.<ref>PMID:16321938</ref> | ||
== Structural highlights == | |||
CcpA phosphorylation activity is carried out by a phosphorylated Ser residue. | |||
</StructureSection> | </StructureSection> | ||