Autophagy-related protein: Difference between revisions

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 <StructureSection load='3vh3' size='340' side='right' caption='Yeast Atg7 C terminal (grey) complex with Atg8 (green) and Zn+2 ion (grey) (PDB code [[3vh3]])' scene=''>
-'''Autophagy-related proteins''' (Atg) function in autophagosome formation from the pre-autophagosomal structure (PAS).  The phagosomes perform protein degradation under starvation.  Autophagy is the process of forming a vacuole around proteins or nucleic acids destined to be broken down.  This vacuole is a double membrane enclosure called phagophore.  Atgs have non-autophagic functions as well as they are involved in cell survival and apoptosis.  So far 34 Atgs have been identified in yeast. <br />
+'''Autophagy-related proteins''' (Atg) function in autophagosome formation from the pre-autophagosomal structure (PAS).  The phagosomes perform protein degradation under starvation.  Autophagy is the process of forming a vacuole around proteins or nucleic acids destined to be broken down.  This vacuole is a double membrane enclosure called phagophore.  Atgs have non-autophagic functions as well as they are involved in cell survival and apoptosis.<ref>PMID:26382870</ref>  So far 34 Atgs have been identified in yeast. <br />
 *'''Atg1, 6, 14''' are involved in the formation of the phagophore.  <br />
 *'''Atg3''' catalyzes the conjugation of Atg8 and phosphatidylethanolamine.  This conjugation is essential for autophagosome formation. <br />