1j3c: Difference between revisions
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==Solution structure of the C-terminal domain of the HMGB2== | ==Solution structure of the C-terminal domain of the HMGB2== | ||
<StructureSection load='1j3c' size='340' side='right' caption='[[1j3c]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''> | <StructureSection load='1j3c' size='340' side='right' caption='[[1j3c]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1j3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J3C FirstGlance]. <br> | <table><tr><td colspan='2'>[[1j3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J3C FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3c OCA], [http://pdbe.org/1j3c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1j3c RCSB], [http://www.ebi.ac.uk/pdbsum/1j3c PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3c OCA], [http://pdbe.org/1j3c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1j3c RCSB], [http://www.ebi.ac.uk/pdbsum/1j3c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1j3c ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j3c ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
Revision as of 12:55, 4 October 2017
Solution structure of the C-terminal domain of the HMGB2Solution structure of the C-terminal domain of the HMGB2
Structural highlights
Function[HMGB2_PIG] DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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